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Two drugs are better than number one

For school-age kids who still wet the bed—a condition called primary nocturnal enuresis—two drugs may be better than one for staying dry at night. In a study of 145 children ages 6 to 15 with a history of at least three wet nights a week, doctors found that combining two drugs, desmopressin (an antidiuretic hormone) with oxybutynin (an antispasmodic used to treat overactive bladder) yielded the best and most rapid results when compared to other drugs used alone. Most kids outgrow the problem by their teen years, and nondrug treatments often include behavior modifications like scheduling bathroom trips, limiting fluids and using alarm devices.